atg-16.1 Antibody
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In Stock 
Product Specs
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
atg-16.1 antibody; F02E8.5Autophagic-related protein 16.1 antibody
Target Names
atg-16.1
Uniprot No.
Target Background
Function
This antibody targets ATG-16.1, a protein likely involved in the formation of the ATG-5-ATG-12-ATG-16.1/ATG-16.2 complex. This complex is recruited to the preautophagosomal membrane and interacts with LGG-2 to facilitate autophagosome formation. While ATG-16.1 may play a distinct role in autophagosome formation compared to ATG-16.2, it functions in a partially redundant manner with ATG-16.2 to regulate autophagic processes.
Database Links
Protein Families
WD repeat tipD family
Subcellular Location
Cytoplasm.
Tissue Specificity
Expressed in neurons, pharyngeal muscles, body wall muscle cells and intestinal cells.
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