At2g18193 Antibody

Protein Localization and Expression Profiling

The antibody enables detection of At2g18193 under stress conditions. For example:

• High-Light Stress: RNA-seq data revealed that At2g18193 expression was repressed in the ilp1-1 mutant during prolonged high-light exposure, suggesting its role in photoprotective mechanisms .

• Pathogen Response: While not directly tested for At2g18193, analogous AAA-ATPases are implicated in plant immune signaling .

Transcriptional Regulation Under Stress

A 2023 study using RNA-seq highlighted dynamic At2g18193 expression patterns:

Functional Insights

• AAA-ATPase Activity: The protein’s ATP-binding domain (residues 200–300) is conserved across plant species, implying a role in energy-dependent processes like protein complex disassembly .

• Genetic Redundancy: Dual annotation (At2g18190/At2g18193) complicates functional studies, necessitating antibody-based protein-level validation .

Limitations and Future Directions

• Specificity Challenges: Cross-reactivity with homologous AAA-ATPases (e.g., At2g18190) remains unverified .

• Therapeutic Potential: No studies yet explore agricultural applications, though analogous antibodies are used in crop pathogen diagnostics .