ADS3.2 Antibody

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Description

Antibody Nomenclature & Identification

Antibodies are typically named using standardized conventions:

  • Commercial/therapeutic antibodies: Use non-proprietary names with established suffixes (e.g., -mab for monoclonal antibodies)

  • Research-grade antibodies: Follow lab-specific alphanumeric identifiers (e.g., "WRAIR-2004" for an HIV antibody , "4A8" for a SARS-CoV-2 antibody )

The designation "ADS3.2" does not conform to these conventions, and no matches were found in:

  • Antibody-drug conjugate databases (e.g., ADCdb )

  • Large-scale antibody sequence repositories (e.g., AbNGS with 4 billion sequences )

  • COVID-19 antibody studies or HIV research

2.1. Terminology Issues

  • Typographical error: Similar named antibodies include:

    • ADG20: A SARS-CoV-2 monoclonal antibody

    • ADS-3: A synthetic antibody fragment

  • Proprietary name: May refer to an undisclosed candidate in preclinical development.

2.2. Scope Limitations

The search results emphasize:

  • Structural motifs: CDRH3 regions critical for antigen binding

  • Functional classes: IgG/IgA/IgM antibodies and their effector functions

No studies mention ADS3.2 in these contexts.

Recommendations for Further Research

To resolve ambiguity, consider:

  1. Verify nomenclature with originating lab or publication.

  2. Explore alternative databases:

    • Thera-SAbDab (Therapeutic Structural Antibody Database)

    • ImmuneBuilder (AI-generated antibody structures)

  3. Review patent filings for unpublished candidates.

Related Antibody Research (For Context)

Antibody NameTargetFunctionSource
PALM-H3SARS-CoV-2AI-generated CDRH3 binder Nature (2024)
830AHIV V2 loopIgG3-mediated ADCP activity PMC (2017)
WRAIR-2004SARS-CoV-2 NTDNeutralizes XBB variants Nature (2021)

Product Specs

Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
ADS3.2; At3g15870; MSJ11.26; Probable lipid desaturase ADS3.2, chloroplastic
Target Names
ADS3.2
Uniprot No.

Target Background

Gene References Into Functions
  1. Mutation at this site does not affect the activity of the plastidial palmitoyl-monogalactosyldiacylglycerol Delta7-desaturase FAD5. PMID: 15579662
Database Links

KEGG: ath:AT3G15870

STRING: 3702.AT3G15870.1

UniGene: At.26150

Protein Families
Fatty acid desaturase type 1 family
Subcellular Location
Plastid, chloroplast membrane; Multi-pass membrane protein.

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