ALB4 Antibody

Albumin Antibody Overview

Albumin antibodies are critical tools for detecting serum albumin (ALB), the most abundant plasma protein responsible for maintaining osmotic pressure, transporting molecules, and regulating metabolic processes . Commercial antibodies target specific epitopes across species (human, mouse, rat) and are validated for applications including Western blot (WB), immunohistochemistry (IHC), and ELISA .

Key Albumin Antibodies in Research

The following table summarizes prominent monoclonal and polyclonal albumin antibodies from peer-reviewed sources and commercial vendors:

Challenges in Identifying "ALB4 Antibody"

• Nomenclature Ambiguity: "ALB4" does not align with standardized antibody naming conventions (e.g., clone IDs like F-8 or catalog numbers like PACO24612) .

• Database Gaps: Thera-SAbDab, a therapeutic antibody database, catalogs ~500 antibody-related therapies but lists no entries for ALB4 .

• Commercial Absence: Major vendors (Santa Cruz Biotechnology, Abcam, R&D Systems) show no ALB4-specific products .

Research Recommendations

To investigate uncharacterized albumin antibodies:

1. Sequence Alignment: Compare variable domain sequences against structural databases like SAbDab .

2. Functional Screens: Validate cross-reactivity using techniques such as Simple Western™ or RNAscope®ISH .

3. Therapeutic Profiling: Assess FcRn interactions if targeting albumin homeostasis .