ATAD1 Antibody
Shipped with Ice Packs 
In Stock 
Product Specs
Buffer
Preservative: 0.03% ProClin 300
Components: 50% Glycerol, 0.01M PBS, pH 7.4
Components: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Orders are typically dispatched within 1-3 business days of receipt. Delivery times may vary depending on the shipping method and destination. Please contact your local distributor for precise delivery estimates.
Synonyms
4921525H23Rik antibody; AAA+ ATPase Thorase antibody; Ab2-088 antibody; AFDC1 antibody; Atad1 antibody; ATAD1_HUMAN antibody; ATPase family AAA domain containing protein 1 antibody; ATPase family AAA domain-containing protein 1 antibody; ATPase family, AAA domain containing 1 antibody; ATPase Thorase antibody; AW107648 antibody; FLJ14600 antibody; FNP001 antibody; Thorase antibody
Target Names
ATAD1
Uniprot No.
Target Background
Function
ATAD1 is an outer mitochondrial translocase essential for the removal of mislocalized tail-anchored transmembrane proteins from mitochondria. It specifically recognizes and binds these proteins, acting as a dislocase to mediate their ATP-dependent extraction from the outer mitochondrial membrane. Furthermore, ATAD1 plays a crucial role in regulating the surface expression of AMPA receptors (AMPARs), thereby influencing synaptic plasticity, learning, and memory. Specifically, it is required for NMDA-stimulated AMPAR internalization and inhibits the recycling of GRIA1 and GRIA2 back to the plasma membrane; these functions are ATPase-dependent.
Database Links
Protein Families
AAA ATPase family
Subcellular Location
Mitochondrion outer membrane; Single-pass membrane protein. Peroxisome membrane; Single-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Single-pass membrane protein.
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