AVT6A Antibody
Description
Introduction to Antibodies
Antibodies, also known as immunoglobulins, are large glycoproteins produced by B cells in the immune system. They play a crucial role in recognizing and binding to specific antigens, which helps in neutralizing pathogens and foreign substances in the body .
Structure of Antibodies
Antibodies consist of four polypeptide chains: two heavy chains and two light chains, arranged in a Y-shaped structure. The variable regions of both heavy and light chains form the antigen-binding site, which is responsible for the specificity of the antibody .
Types of Antibodies
There are several classes of antibodies, including IgG, IgM, IgA, IgE, and IgD, each with distinct functions and properties . For example, IgG is the most abundant antibody in serum and provides long-term immunity, while IgE is involved in allergic reactions .
Antibody Applications
Antibodies are used in various therapeutic and diagnostic applications. Monoclonal antibodies, for instance, have been effective in treating diseases like cancer and autoimmune disorders by targeting specific antigens .
Research on Specific Antibodies
While there is no specific information on "AVT6A Antibody," research on antibodies often involves studying their structure, function, and applications in medicine. For example, studies on adeno-associated virus (AAV) antibodies focus on their impact on gene therapy efficacy .
Data Tables
Since specific data on "AVT6A Antibody" is not available, here is a general table summarizing the characteristics of different antibody classes:
| Antibody Class | Heavy Chain Class | Molecular Weight (kDa) | % Total Serum Antibody | Functional Properties |
|---|---|---|---|---|
| IgM | μ (mu) | 900 | 6 | First line of defense |
| IgG | γ (gamma) | 150 | 80 | Long-term immunity |
| IgA | α (alpha) | 385 | 13 | Mucosal immunity |
| IgE | ε (epsilon) | 200 | 0.002 | Allergic reactions |
| IgD | δ (delta) | 180 | 1 | Antigen recognition |
References
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Bio-Techne. Antibody Basics: What are Antibodies and What Do They Do? [Accessed 2024].
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Pan and colleagues. A sensitive AAV transduction inhibition assay assists evaluation of pre-existing AAV immunity. [PMC, 2023].
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Design, synthesis, and biological evaluation of AV6 derivatives. [PMC, 2018].
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Creative Proteomics. Antibody Heavy and Light Chains: Structure and Function. [Accessed 2024].
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Binding and neutralizing anti-AAV antibodies. [PubMed, 2023].
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Identification and Validation of Small Molecules That Enhance Recombinant Adeno-associated Virus Transduction. [PMC, 2016].
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Jack Westin. Structure Of Antibody Molecule - Immune System - MCAT Content. [Accessed 2024].
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Pharmacy Times. Study: Monoclonal Antibodies Benefit Those Previously Treated for HIV. [Accessed 2024].
