BBX25 Antibody

Shipped with Ice Packs
In Stock

Product Specs

Buffer
Preservative: 0.03% ProClin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
14-16 weeks (made-to-order)
Synonyms
BBX25 antibody; STH antibody; STH1 antibody; At2g31380 antibody; T28P16.13B-box zinc finger protein 25 antibody; Protein SALT TOLERANCE HOMOLOG 1 antibody; Salt tolerance-like protein antibody
Target Names
BBX25
Uniprot No.

Target Background

Function
BBX25 (also known as STH) acts as a negative regulator of seedling photomorphogenesis. It functions as a transcriptional corepressor, alongside BBX24 (STO), inhibiting HY5 activity and consequently downregulating BBX22 expression. This BBX25/BBX24-mediated repression plays a significant role in de-etiolation and the hypocotyl shade avoidance response, with BBX25 and BBX24 exhibiting additive effects in these processes.
Gene References Into Functions
  • BBX24 and BBX25 physically interact with HYH, depleting the active pool of HYH molecules and indirectly reducing HY5 function in promoting photomorphogenesis. [BBX25] PMID: 23733077
  • BBX25 (At2g31380) and BBX24 (At1g06040) function as transcriptional corepressors, likely by forming inactive heterodimers with HY5 (At5g11260). This interaction downregulates BBX22 (AT1G78600) expression, impacting light-mediated seedling development. PMID: 23624715
Database Links

KEGG: ath:AT2G31380

STRING: 3702.AT2G31380.1

UniGene: At.24192

Subcellular Location
Nucleus.

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