At4g14600 Antibody

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Description

Introduction to At4g14600 Antibody

The At4g14600 Antibody (Catalog Code: CSB-PA837770XA01DOA) is a polyclonal antibody developed for research applications targeting the At4g14600 protein in Arabidopsis thaliana (mouse-ear cress). This antibody is part of a broader portfolio of plant-specific reagents designed to study protein localization, function, and interactions in plant biology. Below is a detailed breakdown of its specifications and potential applications, synthesized from available data.

Research Context and Potential Applications

While no peer-reviewed studies explicitly detail the use of the At4g14600 Antibody, its development aligns with broader trends in plant antibody research. Arabidopsis antibodies are critical for:

  • Protein localization studies: Immunofluorescence or immunoblotting to map protein distribution in tissues like pollen tubes or root cells.

  • Functional studies: Knockdown or overexpression experiments to assess phenotypic changes (e.g., root growth, stress responses) .

  • Interaction mapping: Co-immunoprecipitation (Co-IP) to identify binding partners in cellular pathways.

For example, antibodies targeting syntaxins (e.g., AtSYP31/32) have been used to study pollen wall development, vesicle trafficking, and cell wall integrity in Arabidopsis . While not directly involving At4g14600, these studies illustrate the methodologies applicable to similar antibodies.

Limitations and Gaps in Current Data

Key limitations include:

  1. No Published Validation Data: The provided sources do not include immunoblot, immunofluorescence, or ELISA validation for the At4g14600 Antibody.

  2. Functional Context Unclear: The gene At4g14600 encodes a hypothetical protein with limited annotated functional data in public databases (e.g., TAIR, UniProt).

  3. Species Specificity: The antibody is described for Arabidopsis only; cross-reactivity with other plant species is unverified.

Product Specs

Buffer
Preservative: 0.03% ProClin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
14-16 weeks (Made-to-order)
Synonyms
At4g14600 antibody; dl3340w antibody; FCAALL.126Bet1-like protein At4g14600 antibody
Target Names
At4g14600
Uniprot No.

Target Background

Function
Essential for vesicular transport between the endoplasmic reticulum (ER) and the Golgi apparatus. It functions as a SNARE protein associated with ER-derived vesicles.
Database Links

KEGG: ath:AT4G14600

STRING: 3702.AT4G14600.1

UniGene: At.33264

Protein Families
BET1 family
Subcellular Location
Golgi apparatus membrane; Single-pass type IV membrane protein. Endoplasmic reticulum membrane; Single-pass type IV membrane protein.

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