BHLH34 Antibody

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Description

Understanding bHLH34

bHLH34 is a transcription factor in Arabidopsis thaliana that plays a role in stress responses, including glucose, abscisic acid (ABA), salt, and osmotic stress . It is involved in regulating iron homeostasis by activating other transcription factors under iron deficiency conditions . The function of bHLH34 has been studied through overexpression and RNA interference (RNAi) experiments in Arabidopsis plants .

Research Findings on Related Topics

While there is no direct information on "BHLH34 Antibody," research on related topics provides insights into how antibodies and transcription factors are studied:

  • VH4-34 Antibodies: These are human antibodies associated with autoreactivity and autoimmune diseases. They are more frequently found in B1 cells than in other B cell populations .

  • bHLH34 in Plants: This transcription factor is involved in stress responses and iron homeostasis in Arabidopsis .

  • Bhlhe40 in Immunity: A transcription factor involved in regulating immunity and autoimmunity in mammals .

Data Tables

Since there is no specific data available for "BHLH34 Antibody," we can consider a hypothetical table structure for antibodies in general:

Antibody TypeTargetApplication
VH4-34 AntibodiesAutoantigensAutoimmune Disease Research
bHLH34-relatedbHLH34Plant Stress Response Studies

This table illustrates how antibodies can be categorized based on their targets and applications.

References Frontiers in Immunology: Human VH4-34 antibodies derived from B1 cells are more frequently autoreactive. Frontiers in Plant Science: Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose-Mediated Stress Response. PMC: The transcription factor Bhlhe40 in immunity and autoimmunity. PMC: Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis.

Product Specs

Buffer
Preservative: 0.03% ProClin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
14-16 weeks (made-to-order)
Synonyms
BHLH34 antibody; EN135 antibody; At3g23210 antibody; K14B15.12Transcription factor bHLH34 antibody; Basic helix-loop-helix protein 34 antibody; AtbHLH34 antibody; bHLH 34 antibody; Transcription factor EN 135 antibody; bHLH transcription factor bHLH034 antibody
Target Names
BHLH34
Uniprot No.

Target Background

Gene References Into Functions
The following genes function as homodimers or heterodimers to non-redundantly regulate iron homeostasis: 1. bHLH34, bHLH104, and bHLH105 (IAA-LEUCINE RESISTANT3). [PMID: 26921305](https://www.ncbi.nlm.nih.gov/pubmed/26921305)
Database Links

KEGG: ath:AT3G23210

STRING: 3702.AT3G23210.1

UniGene: At.6338

Subcellular Location
Nucleus.
Tissue Specificity
Expressed constitutively in roots, leaves, stems, and flowers.

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