BHLH77 Antibody

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Description

Understanding Antibodies

Antibodies, or immunoglobulins, are proteins produced by B cells that play a crucial role in the immune system by recognizing and binding to specific antigens. There are five main classes of antibodies: IgG, IgM, IgA, IgD, and IgE, each with distinct functions and characteristics . Antibodies can be used in various applications, including diagnostics, therapeutics, and research tools.

Monoclonal Antibodies

Monoclonal antibodies are engineered to target specific antigens and have been widely used in cancer treatment, autoimmune diseases, and viral infections. For example, monoclonal antibodies have shown promise in HIV treatment by suppressing the virus for extended periods . They are also being explored for their potential in treating respiratory infections like parainfluenza virus .

VHH Antibodies

VHHs (Variable Heavy Chain) antibodies, derived from camelids, are smaller and more versatile than traditional antibodies. They have applications in cancer diagnosis and treatment due to their low immunogenicity and ability to penetrate tissues effectively .

Research Findings and Data

While specific data on the "BHLH77 Antibody" is not available, research in the field of antibodies continues to advance with significant findings:

Antibody TypeApplicationKey Features
Monoclonal AntibodiesHIV TreatmentLong-term viral suppression
VHH AntibodiesCancer Diagnosis/TreatmentLow immunogenicity, high tissue penetration
IgG AntibodiesImmune ResponseNeutralization, opsonization, complement activation

References Jackson ImmunoResearch. (2025). Immunoglobulin Classes. Harvard Medical School. (2024). New Insights on B Cells. PMC. (2024). An Integrated Database of Experimentally Validated Major Histocompatibility Complex Epitopes for Antigen-Specific Cancer Therapy. Sigma-Aldrich. Blood Typing Monoclonal Antibodies FFMU. Pharmacy Times. (2023). Study: Monoclonal Antibodies Benefit Those Previously Treated for HIV. PMC. (2024). Promising Diagnostic and Therapeutic Approaches Based on VHHs for Cancer Management. UniProt. Transcription factor bHLH77 - Arabidopsis thaliana. Vanderbilt University Medical Center. (2024). Scientists Find Antibodies That Block Parainfluenza Virus Infection. PMC. (2019). Highlights of 2019 Protein Engineering Summit (PEGS) in Boston, USA.

Product Specs

Buffer
Preservative: 0.03% ProClin 300; Constituents: 50% Glycerol, 0.01M Phosphate Buffered Saline (PBS), pH 7.4
Form
Liquid
Lead Time
14-16 week lead time (made-to-order)
Synonyms
BHLH77 antibody; ACE3 antibody; EN87 antibody; At3g23690 antibody; MYM9.3 antibody; Transcription factor bHLH77 antibody; Basic helix-loop-helix protein 77 antibody; AtbHLH77 antibody; bHLH 77 antibody; Protein ACTIVATOR FOR CELL ELONGATION 3 antibody; Transcription factor EN 87 antibody; bHLH transcription factor bHLH077 antibody
Target Names
BHLH77
Uniprot No.

Target Background

Database Links

KEGG: ath:AT3G23690

STRING: 3702.AT3G23690.1

UniGene: At.6666

Subcellular Location
Nucleus.
Tissue Specificity
Expressed constitutively in roots, leaves, stems, and flowers.

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