BRXL2 Antibody

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Description

BRXL2 Protein in Plant Biology

BRXL2 is a protein that plays a crucial role in the establishment and maintenance of cell polarity during asymmetric cell divisions in plants. It is known to polarize earlier than another protein called BASL and remains polarized longer after the formation of the new cell wall . This polarization is essential for the proper development and differentiation of plant cells.

Key Findings on BRXL2 Dynamics

  • Polarization Timing: BRXL2 becomes polarized approximately 5 hours before the formation of the new cell wall and remains polarized for over 9 hours afterward .

  • Comparison with BASL: BRXL2 polarizes earlier and stays polarized longer than BASL during ACDs .

  • Interaction with Other Proteins: BRXL2 interacts with KIPK, a kinase involved in hypocotyl gravitropism, and can be phosphorylated by KIPK .

Antibodies in Research

Antibodies are proteins produced by B cells that bind specifically to antigens. They are used extensively in research for detecting and quantifying proteins, including those involved in plant biology. While there is no specific mention of a "BRXL2 Antibody" in the literature, antibodies are crucial tools for studying protein localization and function in cells.

Characteristics of Antibodies

  • Structure: Antibodies are composed of two heavy chains and two light chains, forming a Y-shaped structure .

  • Function: They bind to specific epitopes on antigens, allowing for the detection and analysis of proteins in various biological samples .

  • Types: Antibodies can be polyclonal or monoclonal, each with different applications in research and diagnostics .

Potential Use of Antibodies in Plant Biology

In plant biology, antibodies could be used to study proteins like BRXL2 by detecting their localization and expression levels in plant cells. This would involve developing specific antibodies against BRXL2 or using existing antibodies against related proteins to understand their roles in plant development.

Potential Applications

  • Immunolocalization: Antibodies can be used to visualize the localization of BRXL2 in plant cells, providing insights into its role in cell polarity and development.

  • Western Blotting: Antibodies can quantify BRXL2 expression levels in different plant tissues or developmental stages.

Data Table: Comparison of BRXL2 and BASL Dynamics

FeatureBRXL2BASL
Polarization TimingPolarizes earlierPolarizes later
Duration of PolarityRemains polarized longerShorter duration of polarity
Function in ACDEssential for cell polarity establishmentInvolved in cell fate specification

This table highlights the differences in polarization dynamics between BRXL2 and BASL during asymmetric cell divisions in plants.

References Quantitative and dynamic cell polarity tracking in plant cells. PMC, 2021. bcl-2 Antibody (EP36) - Bio SB, 2022. Biological screening of a unique drug library targeting MRGPRX2. Frontiers in Immunology, 2022. Antibody: Definition, Structure, Types, Forms, Functions. Microbenotes, 2024. KIPK and KIPK-LIKE1 suppress overbending during negative hypocotyl gravitropism. bioRxiv, 2024. A Potent and Highly Efficacious Bcl-2/Bcl-xL Inhibitor. PMC, 2013. Antibody Structure - Biology LibreTexts. Prince George's Community College.

Product Specs

Buffer
Preservative: 0.03% ProClin 300; Constituents: 50% Glycerol, 0.01M Phosphate Buffered Saline (PBS), pH 7.4
Form
Liquid
Lead Time
14-16 week lead time (made-to-order)
Synonyms
BRXL2 antibody; At3g14000 antibody; MDC16.12 antibody; MDC16.13Protein Brevis radix-like 2 antibody; AtBRXL2 antibody
Target Names
BRXL2
Uniprot No.

Target Background

Database Links

KEGG: ath:AT3G14000

STRING: 3702.AT3G14000.1

UniGene: At.39306

Protein Families
BRX family
Subcellular Location
Nucleus.
Tissue Specificity
Expressed in roots.

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