C11orf70 Antibody

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In Stock

Product Specs

Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. Store at -20°C. Avoid freeze / thaw cycles.
Lead Time
Typically, we can ship your order within 1-3 business days after receiving it. Delivery times may vary depending on the purchasing method or location. Please consult your local distributor for specific delivery details.
Synonyms
CFAP300 antibody; C11orf70Cilia- and flagella-associated protein 300 antibody
Target Names
C11orf70
Uniprot No.

Target Background

Function
C11orf70 is a protein specifically found in cilia and flagella. It plays a crucial role in organizing the structure of axonemes and regulating their motility. C11orf70 may also contribute to the assembly of both outer and inner dynein arms.
Gene References Into Functions
  1. C11orf70 is essential for the assembly of dynein arms. Mutations in C11orf70 can lead to defective cilia motility and Primary ciliary dyskinesia. PMID: 29727692
  2. C11orf70 acts as a preassembly factor, playing a role in the pathogenesis of Primary ciliary dyskinesia. PMID: 29727693
Database Links

HGNC: 28188

KEGG: hsa:85016

STRING: 9606.ENSP00000414390

UniGene: Hs.98328

Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton, cilium axoneme.
Tissue Specificity
Expressed in nasal epithelial cells.

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