At3g55980 Antibody

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Description

Introduction to At3g55980 Antibody

The At3g55980 antibody (Product Code: CSB-PA835968XA01DOA) is a research tool developed to study the At3g55980 gene product, a protein involved in plant stress responses and RNA splicing . It is commercially available for use in molecular biology applications, particularly in Arabidopsis research.

Role in Salt Stress Resistance

  • The At3g55980 gene (SZF1) is critical for salt stress tolerance in Arabidopsis. Mutants lacking functional At3g55980 exhibit altered splicing patterns in stress-related genes, impairing their ability to respond to environmental challenges .

Splicing Regulation

  • Alternative splicing of At3g55980 pre-mRNA is influenced by:

    • Mutations in splicing factors (e.g., AtU2AF65a/b and AtSF1) .

    • Lower ambient growth temperatures .

Applications in Scientific Research

While specific protocols are not detailed in the provided sources, the antibody’s utility likely includes:

  • Mechanistic studies of salt stress responses.

  • Splicing regulation analysis in plant mutants.

  • Protein localization via immunohistochemistry or fluorescent tagging (inferred from typical antibody uses in plant research) .

Future Research Directions

Further studies could explore:

  • The structural basis of At3g55980’s role in spliceosome assembly.

  • Interactions with other splicing factors (e.g., AtU2AF65a/b) under stress conditions .

  • Development of transgenic Arabidopsis lines to validate antibody specificity.

Product Specs

Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
At3g55980 antibody; F27K19.160Zinc finger CCCH domain-containing protein 47 antibody; AtC3H47 antibody; AtSZF1 antibody
Target Names
At3g55980
Uniprot No.

Target Background

Function
This protein is involved in the plant's response to salt stress. It may positively modulate plant tolerance to salt stress.
Gene References Into Functions
  1. AtSZF1 and AtSZF2 negatively regulate the expression of salt-responsive genes. They play crucial roles in modulating the tolerance of Arabidopsis plants to salt stress. [AtSZF1] PMID: 17609218
Database Links

KEGG: ath:AT3G55980

STRING: 3702.AT3G55980.1

UniGene: At.21697

Subcellular Location
Nucleus.
Tissue Specificity
Expressed in roots and anthers.

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