zgc:112163 Antibody

Gene Expression Correlations of zgc:112163

Gene expression profiling in zebrafish tissues reveals associations with other genes, indicating potential functional pathways (Table 1) .

Table 1: Correlated gene expression with zgc:112163 in zebrafish

Key observations:

• Positive correlates include transporters (e.g., slc39a8) and uncharacterized loci (e.g., LOC101882645), suggesting roles in metal ion homeostasis or developmental processes.

• Negative correlates involve cell adhesion molecules (e.g., cldni, epcam), hinting at regulatory antagonism in epithelial or endothelial functions.

Zebrafish as a Model Organism

• Zebrafish genes like zgc:112163 are frequently studied in developmental biology due to their transparency and genetic tractability.

• Antibodies targeting zebrafish proteins enable spatial and temporal tracking of gene expression during embryogenesis .

Limitations and Future Directions

• Knowledge gaps: The biological role of zgc:112163 remains undefined. Knockout models paired with this antibody could clarify its involvement in zebrafish development or disease.

• Technical considerations: Antibody validation in peer-reviewed studies is absent, necessitating independent verification for experimental reliability.

Comparative Antibody Repertoire Insights

Although not directly related to zgc:112163, recent advances in antibody genomics highlight:

• V-gene allelic polymorphisms significantly impact antigen binding, as shown in SARS-CoV-2 and influenza antibodies .

• D-D fusions and inverted D genes expand combinatorial diversity in human antibodies , underscoring the need for similar explorations in zebrafish immunology.