CAT2 Antibody
Description
Introduction to CAT2 Antibody
The CAT2 antibody is primarily associated with two distinct proteins: Catalase 2 and Cationic Amino Acid Transporter 2 (CAT2). This article will focus on both aspects, providing a comprehensive overview of the CAT2 antibody related to these proteins.
Catalase 2 (CAT2) Antibody
Catalase 2 is an enzyme found in plants like Arabidopsis thaliana, where it plays a crucial role in the detoxification of hydrogen peroxide (H2O2) by converting it into water and oxygen. The CAT2 antibody is used to detect this enzyme in various plant species.
Cationic Amino Acid Transporter 2 (CAT2) Antibody
Cationic Amino Acid Transporter 2 is involved in the transport of cationic amino acids, such as arginine, across cell membranes. It is significant in immune responses and has been studied in the context of its role in regulating nitric oxide production and immune cell function.
Catalase 2 (CAT2) Antibody Characteristics
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Immunogen: Full-length, recombinant catalase 2 from Arabidopsis thaliana (UniProt: P25819, TAIR: At4g35090) .
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Reactivity: Confirmed reactivity with Arabidopsis thaliana, Brassica napus, and Oryza sativa. Predicted reactivity includes Cannabis sativa, Gossypium hirsutum, Salicornia brachiata, and Theobroma cacao .
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Applications: Western blot (WB) with a recommended dilution of 1:1000 .
Cationic Amino Acid Transporter 2 (CAT2) Antibody Characteristics
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Function: Involved in the transport of L-arginine, crucial for nitric oxide production and immune cell function .
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Applications: Research on immune responses, particularly in the context of infections and inflammation .
Catalase 2 (CAT2) Research
Catalase 2 plays a vital role in plant stress responses by detoxifying hydrogen peroxide. The CAT2 antibody is used to study the expression and localization of catalase 2 in plant tissues.
| Species | Reactivity | Predicted Reactivity |
|---|---|---|
| Arabidopsis thaliana | Confirmed | - |
| Brassica napus | Confirmed | - |
| Oryza sativa | Confirmed | - |
| Cannabis sativa | Predicted | - |
| Gossypium hirsutum | Predicted | - |
| Salicornia brachiata | Predicted | - |
| Theobroma cacao | Predicted | - |
Cationic Amino Acid Transporter 2 (CAT2) Research
CAT2 is essential for the transport of L-arginine, which is crucial for nitric oxide production and immune cell function. Studies have shown that CAT2-deficient mice exhibit impaired immune responses, including increased susceptibility to infections and exacerbated disease conditions .
| Function | Impact of CAT2 Deficiency |
|---|---|
| L-arginine transport | Reduced intracellular L-arginine levels |
| Nitric oxide production | Impaired |
| Immune cell function | Diminished suppressive activity of MDSCs |
| Disease susceptibility | Increased susceptibility to infections like Schistosoma mansoni and Toxoplasma gondii |
