The CCR4-NOT complex, of which this antibody's target is a catalytic component, functions as a general transcription factor within the nucleus and as the primary mRNA deadenylase responsible for mRNA turnover in the cytoplasm.
Gene References Into Functions
In Arabidopsis thaliana, AtCCR4a and AtCCR4b are localized to cytoplasmic processing bodies (P-bodies) and participate in sucrose and starch metabolism. These isoforms also regulate the poly(A) tail length of the Granule-bound starch synthase 1 (GBSS1) transcript. [AtCCR4a] PMID: 25630334