hsp-60 Antibody

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Product Specs

Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
hsp-60 antibody; hsp60 antibody; Y22D7AL.5Chaperonin homolog Hsp-60 antibody; mitochondrial antibody; Heat shock protein 60 antibody; HSP-60 antibody
Target Names
hsp-60
Uniprot No.

Target Background

Function

HSP-60 is a molecular chaperone implicated in mitochondrial protein import and macromolecular assembly. It facilitates the correct folding of imported proteins. Additionally, HSP-60 may prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.

Gene References Into Functions
  1. Cytosol-localized HSP-60 physically binds and stabilizes SEK-1/MAP kinase kinase 3, which in turn up-regulates p38 MAP kinase and increases immunity. PMID: 28283579
Database Links
Protein Families
Chaperonin (HSP60) family
Subcellular Location
Mitochondrion matrix.

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