The term "CHX24" does not correspond to any recognized gene, protein, or antibody in biological nomenclature. Possible scenarios for this discrepancy include:
Typographical error: The query may reference a misspelled or misformatted term (e.g., CHD2, CHD4, or CXCL24).
Proprietary name: "CHX24" could be an internal code for an unpublished or commercial antibody not yet cataloged in public databases.
CHD2 (Chromodomain Helicase DNA-Binding Protein 2) is a well-characterized epigenetic regulator. Key antibodies targeting CHD2 include:
CHD2 antibodies are widely used in chromatin remodeling studies and neurological disorder research .
CHD4, a paralog of CHD2, is implicated in DNA repair and cancer. Notable antibodies:
CHD4 antibodies detect isoforms involved in the NuRD complex, critical for gene silencing and DNA damage response .
If the query refers to a novel or proprietary antibody, the following steps are recommended for verification:
Reagent validation: Cross-check with manufacturers (e.g., Thermo Fisher, Abcam, CST) for unpublished catalog entries.
Epitope mapping: Confirm if "CHX24" targets a specific domain (e.g., CHD2’s helicase region or CHD4’s chromodomain).
Clinical relevance: Explore associations with diseases (e.g., cancer, neurodegenerative disorders) in preprint repositories like bioRxiv.
KEGG: ath:AT5G37060
STRING: 3702.AT5G37060.1