CIPK7 Antibody

CIPK7 in Plant Signaling Pathways

CIPK7 belongs to the CBL-interacting protein kinase family, which mediates calcium-dependent responses to environmental stresses in plants. Key characteristics include:

• Structural classification:

  • Grouped under intron-poor CIPKs with 0–1 introns ( )

  • Contains a conserved NAF/FISL domain for interaction with CBL proteins ( )

• Functional roles:

  • Cold stress response: Interacts with CBL1 to regulate cold tolerance in Arabidopsis ( )

  • Nutrient stress adaptation: Activated under high carbon/low nitrogen conditions ( )

  • Ion homeostasis: Modulates potassium transporters and H+-ATPase activity ( )

Table 1: CIPK7 Interaction Partners and Stress Responses

Table 2: Expression Patterns of CIPK7 Homologs

Molecular Mechanisms

• Phosphorylation dynamics:

  • CIPK7 phosphorylates ATL31 under nutrient stress, enhancing 14-3-3 protein degradation ( ).

  • Required for cold-induced calcium signaling through CBL1 interaction ( ).

• Evolutionary insights:

  • CIPK7 homologs in Brassica rapa show 86.49% sequence identity between paralogs BraCIPK7.1 and BraCIPK7.2 ( ).

  • Divergent NAF/FISL motifs in CIPK7 paralogs suggest functional specialization ( ).

Research Gaps and Opportunities

No commercial CIPK7 antibodies are documented in the provided sources. Current studies rely on:

• Genetic tools: qRT-PCR for expression profiling ( )

• Interaction assays: Yeast two-hybrid and bimolecular fluorescence complementation ( )

Future work should prioritize antibody development to enable protein-level studies of CIPK7 localization and post-translational modifications.