Function
A probable microtubule plus-end tracking protein. It promotes the stabilization of dynamic microtubules and is essential for mitotic and meiotic spindle formation. Specifically, it promotes the polymerization of kinetochore-bound microtubules. Furthermore, it plays a crucial role in cytoplasmic streaming and is essential for embryonic development.
Subcellular Location
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Note=Localized to kinetochores during metaphase, and to the spindle region. Kinetochore localization requires hcp-1 and hcp-2.