F17E5.2 Antibody

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Description

Database and Literature Review

  • Antibody Structure Databases:
    The Antibody Structure Database (AbDb) and Patent and Literature Antibody Database (PLAbDab) catalog thousands of antibodies, including experimental and therapeutic candidates. Neither database lists "F17E5.2" as a registered antibody.

  • Clinical and Preclinical Studies:
    Recent studies on bispecific antibodies , SARS-CoV-2 neutralizing antibodies , and autoimmune antibodies were reviewed, but none mention this identifier.

Nomenclature Considerations

  • Antibodies are typically named using standardized conventions (e.g., "mAb123" for monoclonal antibodies or "VRC07-523LS" for HIV-specific antibodies ). The format "F17E5.2" does not align with established naming systems.

  • Potential typographical errors or outdated identifiers may contribute to the lack of matches.

Research Context

  • If "F17E5.2" refers to an internal research code or unpublished antibody, it would not appear in public databases or literature.

Recommendations for Further Inquiry

To resolve this discrepancy, consider the following steps:

  1. Verify the Identifier:
    Cross-check with specialized antibody databases such as:

    • Thera-SAbDab (Therapeutic Structural Antibody Database)

    • ImmPort (Immunology Database and Analysis Portal)

  2. Consult Recent Publications:
    Search preprint servers (e.g., bioRxiv) or niche journals for emerging studies.

  3. Contact Authors:
    Reach out to research institutions or biotech companies specializing in antibody engineering (e.g., institutions cited in ).

Related Antibodies for Context

While "F17E5.2" remains unidentifiable, below are structurally or functionally relevant antibodies from the search results:

AntibodyTarget/FunctionKey FeatureSource
10E8.4/iMabHIV envelope and CD4Bispecific, broadly neutralizing
ION_300SARS-CoV-2 RBD (non-ACE2 epitope)Neutralizes multiple variants
Fibronectin (A17)Cell-binding domain of fibronectinInhibits integrin-mediated adhesion

Product Specs

Buffer
Preservative: 0.03% Proclin 300
Composition: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
F17E5.2; Probable calcium-binding mitochondrial carrier F17E5.2
Target Names
F17E5.2
Uniprot No.

Target Background

Function
F17E5.2 Antibody targets a calcium-dependent mitochondrial solute carrier.
Database Links

KEGG: cel:CELE_F17E5.2

STRING: 6239.F17E5.2

UniGene: Cel.19859

Protein Families
Mitochondrial carrier (TC 2.A.29) family
Subcellular Location
Mitochondrion inner membrane; Multi-pass membrane protein.

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