The search results extensively describe CR2 (CD21), a complement receptor critical for B-cell activation and immune response modulation . Notable features include:
Recent studies highlight advancements in antibody therapies targeting viral proteins (e.g., spike/nucleocapsid), with comparisons of neutralizing efficacy against variants like Omicron BA.4/5 . For example:
Bamlanivimab/Etesevimab showed lower hospitalization rates (12.7%) vs. Casirivimab/Imdevimab (28.4%) in high-risk patients .
Omicron subvariants evade antibodies via mutations (e.g., L452M/Q, F486V) that reduce neutralization by 4.2-fold compared to earlier strains .
To resolve the ambiguity around "CRRSP21 Antibody":
Verify nomenclature: Cross-check with institutional databases or proprietary catalogs for potential naming variations (e.g., CRISPR-associated proteins, CR1/CR2 isoforms).
Explore CR2-related pathways: Given the prominence of CD21/CR2 in B-cell biology , investigate whether "CRRSP21" relates to CR2 splice variants or signaling partners like CD19/CD81 .
Consult updates: Monitor repositories like ClinicalTrials.gov or preprint servers (e.g., medRxiv) for emerging studies using this term .