CSAD Antibody, FITC conjugated

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Product Specs

Buffer
**Preservative:** 0.03% Proclin 300
**Constituents:** 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Typically, we are able to ship your orders within 1-3 business days of receipt. Delivery time may vary depending on the method of purchase or location. For specific delivery estimates, please consult your local distributor.
Synonyms
Csad antibody; CSAD_HUMAN antibody; CSD antibody; Cysteine sulfinic acid decarboxylase antibody; Cysteine-sulfinate decarboxylase antibody; Sulfinoalanine decarboxylase antibody
Target Names
CSAD
Uniprot No.

Target Background

Function
Catalyzes the decarboxylation of L-aspartate, 3-sulfino-L-alanine (cysteine sulfinic acid), and L-cysteate to beta-alanine, hypotaurine and taurine, respectively. Its preferred substrate is 3-sulfino-L-alanine. This enzyme does not exhibit any decarboxylation activity toward glutamate.
Gene References Into Functions
  1. Taurine biosynthesis in vertebrates involves two structurally related PLP-dependent decarboxylases (cysteine sulfinic acid decarboxylase and glutamic acid decarboxylase like 1). PMID: 26327310
  2. The presence of cysteine inhibited ADC, CSAD and GDC activity. PMID: 22718265
Database Links

HGNC: 18966

OMIM: 616569

KEGG: hsa:51380

STRING: 9606.ENSP00000267085

UniGene: Hs.279815

Protein Families
Group II decarboxylase family
Tissue Specificity
Expressed in liver and brain. Also expressed in both astrocytes and neurons, but lower levels are expressed in astrocytes.

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