At4g15620 Antibody
Description
Overview of At4g15620 Antibody
The At4g15620 antibody (Product Code: CSB-PA517807XA01DOA) is a custom polyclonal antibody developed to target the Arabidopsis thaliana protein encoded by the AT4G15620 gene. This antibody is widely used in plant molecular biology research to investigate the expression, localization, and functional roles of the uncharacterized integral membrane protein AT4G15620, which belongs to the UPF0497 family .
Key specifications of the antibody include:
| Parameter | Detail |
|---|---|
| Target Species | Arabidopsis thaliana |
| Uniprot ID | O23413 |
| Reactivity | Mouse-ear cress (Arabidopsis) |
| Applications | Western Blot, ELISA, IHC |
| Available Sizes | 2 mL / 0.1 mL |
Role in Abscisic Acid (ABA) Signaling
AT4G15620 was identified in a transcriptomic analysis of ABA-regulated genes. Key findings include:
| Experiment | Ratio (Transgenic/Control) | P Value | Functional Annotation |
|---|---|---|---|
| Untreated RL-BK L1 | 0.42 (±0.03) | 9.9E-09 | Integral membrane protein |
| Untreated RL-BK L3 | Not significant | — | No direct ABA pathway link |
This downregulation implies involvement in membrane-associated signaling cascades, though its exact mechanism remains uncharacterized .
Subcellular Localization
Indirect evidence from homology modeling suggests AT4G15620 localizes to plasma membranes or endomembrane systems, consistent with its transmembrane domain architecture .
Comparative Analysis with Related Antibodies
The At4g15620 antibody is part of a broader catalog targeting Arabidopsis proteins. Examples include:
| Antibody Target | Uniprot ID | Key Function |
|---|---|---|
| CSP4 (CSB-PA655036) | Q38896 | Cysteine protease activity |
| DAR4 (CSB-PA880776) | Q9FKN7 | Drought stress response |
| CYTC-2 (CSB-PA871230) | Q9T0G2 | Cytochrome C oxidase assembly |
Future Research Directions
Product Specs
Composition: 50% Glycerol, 0.01M Phosphate Buffered Saline (PBS), pH 7.4
Target Background
KEGG: ath:AT4G15620
UniGene: At.33162
