CST5 Antibody
Shipped with Ice Packs 
In Stock 
Product Specs
Buffer
**Preservative:** 0.03% Proclin 300
**Constituents:** 50% Glycerol, 0.01M PBS, pH 7.4
**Constituents:** 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Typically, we can ship products within 1-3 business days of receiving your order. Delivery times may vary depending on the purchasing method or location. Please consult your local distributors for specific delivery details.
Synonyms
CST 5 antibody; CST5 antibody; Cystatin 5 antibody; Cystatin-5 antibody; Cystatin-D antibody; CystatinD antibody; Cysteine proteinase inhibitor antibody; CYTD_HUMAN antibody; MGC71922 antibody
Target Names
CST5
Uniprot No.
Target Background
Function
Cystatin D is a cysteine proteinase inhibitor that plays a potential protective role against proteinases found in the oral cavity. It exhibits a preferential inhibition order of cathepsin S > cathepsin H > cathepsin L > cathepsin B.
Gene References Into Functions
- Research suggests that CST5 is a crucial mediator of tumor suppression by p53 in colorectal cancer. PMID: 26158294
- These findings indicate an unexpected role for cystatin D within the cell nucleus, controlling the transcription of specific genes involved in essential cellular functions. This may contribute to its protective effect in colon cancer. PMID: 26364852
- Compared to its homologues, cystatin D exhibits an unusual inhibition profile, preferentially inhibiting cathepsin S > cathepsin H > cathepsin L, and demonstrating no inhibition of cathepsin B or pig legumain. PMID: 15728581
- Cystatin D is a potential tumor suppressor gene induced by vitamin D in human colon cancer cells. PMID: 19662683
Database Links
Protein Families
Cystatin family
Subcellular Location
Secreted.
Tissue Specificity
Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in parotid gland but not in seminal vesicle, prostate, epididymis, testis, ovary, placenta, thyroid, gastric corpus, small intestine, liver, or gall b
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