CTDSPL2 Antibody

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Product Specs

Buffer
Phosphate-buffered saline (PBS) containing 0.1% sodium azide, 50% glycerol, pH 7.3. Store at -20°C. Avoid repeated freeze-thaw cycles.
Lead Time
Typically, we can ship your orders within 1-3 business days of receiving them. Delivery time may vary depending on the purchasing method or location. Please consult your local distributor for specific delivery timelines.
Synonyms
CTD (carboxy-terminal domain; RNA polymerase II; polypeptide A) small phosphatase like 2 antibody; CTD small phosphatase like 2 antibody; CTD small phosphatase like protein 2 antibody; CTD small phosphatase-like protein 2 antibody; CTDSP like 2 antibody; CTDSP-like 2 antibody; ctdspl2 antibody; CTSL2_HUMAN antibody; HSPC058 antibody; HSPC129 antibody
Target Names
CTDSPL2
Uniprot No.

Target Background

Function
CTDSPL2 is likely a phosphatase.
Gene References Into Functions
  • Expression of CTDSPL2 is significantly elevated in the skeletal muscle of chronic kidney disease patients. (PMID: 28506762)
  • CTDSPL2 is a unique chromatin-associated, Ser5-preferential CTD phosphatase that preferentially localizes to transcriptionally silenced gene regions and may play a role in gene regulation during erythroid differentiation. (PMID: 26920047)
  • Proteomic screening was performed to identify binding partners of CTDSPL2 in nuclear extracts through immunoprecipitation of CTDSPL2 with its associated proteins. (PMID: 26674342)
  • CTDSPL2 increases epsilon- and gamma-globin gene expression during erythroid differentiation. (PMID: 20932329)
Database Links

HGNC: 26936

KEGG: hsa:51496

STRING: 9606.ENSP00000260327

UniGene: Hs.497967

Protein Families
CTDSPL2 family

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