F55H2.5 Antibody

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Description

Absence of Primary Evidence for F55HAntibody

  • Database searches: No matches for "F55H2.5 Antibody" were found in PubMed, EMBASE, or antibody-specific repositories like AntibodyRegistry.org .

  • Commercial antibody catalogs: Major suppliers (e.g., Abcam, Active Motif, Thermo Fisher) show no listings for this identifier .

  • Functional characterization: No studies describe its epitope, species reactivity, or applications (e.g., ELISA, IHC, flow cytometry) .

Potential Explanations for the Identifier

The alphanumeric code "F55H2.5" may represent:

  • Lab-specific nomenclature: Internal identifiers from unpublished research (e.g., clone IDs in hybridoma development) .

  • Hypothetical protein annotation: Gene identifiers like "F55H2.5" sometimes appear in genomic databases (e.g., C. elegans ORFs) but lack antibody linkage .

  • Typographical error: Similar valid identifiers (e.g., "5F55" or "H2.5") exist for other antibodies .

Comparative Analysis of Validated Antibodies with Similar Nomenclature

To contextualize the absence of F55H2.5, below are examples of antibodies with systematic naming conventions:

Antibody IDTargetApplicationsKey References
MOAB-2Aβ (amyloid-beta)Alzheimer’s research (IHC, ELISA)
RM2365-hydroxymethylcytosineEpigenetics (MeDIP, flow cytometry)
REGN-COV2 (casirivimab/imdevimab)SARS-CoV-2 spike proteinCOVID-19 therapy (neutralization)

Recommendations for Further Investigation

If "F55H2.5 Antibody" is critical to your research:

  1. Verify the identifier: Confirm spelling, formatting, and institutional sources.

  2. Contact antibody repositories: Inquire about unpublished datasets via platforms like Addgene or ATCC.

  3. Explore homologs: Antibodies targeting similar epitopes (e.g., hypothetical proteins in model organisms) may exist under alternative names .

Technical Considerations for Antibody Validation

While F55H2.5 remains uncharacterized, general best practices for antibody usage include:

  • Specificity: Use knockout/knockdown controls to confirm target binding .

  • Lot validation: Ensure consistency across batches for reproducibility .

  • Application optimization: Titrate concentrations for assays like IHC or flow cytometry .

Product Specs

Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M Phosphate Buffered Saline (PBS), pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
F55H2.5Putative cytochrome b561 antibody; Cytochrome b-561 antibody
Target Names
F55H2.5
Uniprot No.

Target Background

Function
This antibody targets a putative transmembrane reductase. This enzyme utilizes ascorbate as an electron donor in the cytoplasm, facilitating the transfer of electrons across membranes. This process ultimately reduces monodehydro-L-ascorbate radical in the lumen of secretory vesicles.
Database Links

KEGG: cel:CELE_F55H2.5

STRING: 6239.F55H2.5

UniGene: Cel.34525

Subcellular Location
Membrane; Multi-pass membrane protein.

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