dhs-21 Antibody
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In Stock 
Product Specs
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
dhs-21 antibody; R11D1.11L-xylulose reductase antibody; XR antibody; EC 1.1.1.10 antibody; Dicarbonyl/L-xylulose reductase antibody; DCXR antibody; Short-chain dehydrogenase 21 antibody
Target Names
dhs-21
Uniprot No.
Target Background
Function
This antibody catalyzes the NADPH-dependent reduction of several substrates, including L-xylulose, D-xylulose, L-(+) erythrulose, D-erythrose, D-threose, L-ribulose, 1,4-dibromo-2,3-butanedione, and 2,3-heptanedione. It also exhibits activity against isatin, 9,10-phenanthrenequinone, menadione, 2,3-hexaenadione, and 3,4-hexahenadione. Notably, no activity is observed when NADH is used instead of NADPH.
Gene References Into Functions
- Research indicates that DHS-21 is a genuine DCXR in C. elegans, playing a crucial role in maintaining normal lifespan and reproductive function. PMID: 21477590
Database Links
Protein Families
Short-chain dehydrogenases/reductases (SDR) family
Subcellular Location
Cell membrane.
Tissue Specificity
Expressed in intestine, gonad and spermatids (at protein level). Expressed in intestine, uterine seam, gonadal sheath cells, spermathecal-uterus valve and spermatids.
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