LCR35 Antibody
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In Stock 
Description
Clarification of Terminology
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Lcr35: A probiotic strain used in clinical applications for over 50 years, primarily to restore microbial balance in vaginal, intestinal, and immune systems .
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Antibody: A protein produced by the immune system to neutralize pathogens. No studies associate Lcr35 with antibody production or monoclonal antibody development.
Immunomodulatory Mechanisms
Therapeutic Applications
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Vaginal Health: Inhibits Gardnerella vaginalis by modulating SLPI and enhancing epithelial defenses .
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Asthma Prevention: Attenuates airway inflammation via Th2 cytokine suppression (IL-4, IL-5, IL-13) and Treg cell induction .
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Antifungal Activity: Reduces Candida albicans adhesion and biofilm formation via DAF-16/FOXO pathway activation .
Efficacy in Irritable Bowel Syndrome (IBS)
| Parameter | Placebo Group (n=25) | Lcr35 Group (n=25) | P-value |
|---|---|---|---|
| IBS Severity Score | -109.4 ± 93.1 | -56.8 ± 43.9 | NS |
| Abdominal Pain | -61.0 ± 96.0 | -27.5 ± 31.6 | NS |
| NS = Not significant |
Mechanistic Pathways
Product Specs
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M Phosphate Buffered Saline (PBS), pH 7.4
Constituents: 50% Glycerol, 0.01M Phosphate Buffered Saline (PBS), pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
LCR35 antibody; At2g22121 antibody; T16B14Putative defensin-like protein 154 antibody; Putative low-molecular-weight cysteine-rich protein 35 antibody; Protein LCR35 antibody
Target Names
LCR35
Uniprot No.
Target Background
Database Links
Protein Families
DEFL family
Subcellular Location
Secreted.
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