ATTI2 Antibody

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Description

Assessment of Search Results

  • No direct matches for "ATTI2 Antibody" were identified across 12 search results spanning antibody therapeutics, research studies, and regulatory databases.

  • Close nomenclature review:

    • Result references AT-02, a pan-amyloid removal monoclonal antibody developed by Attralus. This is distinct from "ATTI2" and unrelated in target or mechanism.

    • Result discusses monoclonal antibodies targeting ACTR2, but this is a kinase domain unrelated to "ATTI2."

    • Result lists ~150 approved or investigational antibody therapeutics, none aligning with the "ATTI2" designation.

Potential Sources of Ambiguity

  • Typographical errors: "ATTI2" may represent a misspelling or variant of known antibodies (e.g., AT-02, ATTACK2, or ACT-II).

  • Proprietary or developmental code names: Unpublished preclinical compounds often use internal codes not yet disclosed in public databases.

  • Target or epitope mislabeling: If "ATTI2" refers to an antigen (e.g., TROP2, TITIN), further clarification is required.

Recommendations for Further Inquiry

  1. Verify nomenclature: Cross-check with institutional or proprietary databases for typographical corrections.

  2. Explore alternative targets: If "ATTI2" refers to a biomarker (e.g., TROVE2 ), reassess antibody specificity.

  3. Consult regulatory filings: Investigate FDA/EMA clinical trial registries using wildcard terms (e.g., "AT*2 Antibody").

Data Table: Closest Matches in Literature

Antibody NameTargetDeveloperPhaseIndicationSource
AT-02Pan-amyloidAttralusPhase 1Systemic amyloidosis
Ab1SARS-CoV-2 spikeAbound BioPreclinicalCOVID-19 prophylaxis
Anti-TROVE2TROVE2 (Ro60)Research studyN/ARheumatoid arthritis

Product Specs

Buffer
Preservative: 0.03% ProClin 300; Constituents: 50% Glycerol, 0.01M Phosphate Buffered Saline (PBS), pH 7.4
Form
Liquid
Lead Time
14-16 week lead time (made-to-order)
Synonyms
ATTI2 antibody; At2g43520 antibody; T01O24.26 antibody; Defensin-like protein 193 antibody; Trypsin inhibitor ATTI-2 antibody
Target Names
ATTI2
Uniprot No.

Target Background

Database Links

KEGG: ath:AT2G43520

STRING: 3702.AT2G43520.1

UniGene: At.36881

Protein Families
DEFL family, Protease inhibitor I18 (RTI/MTI-2) subfamily
Subcellular Location
Secreted.

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