At2g04046 Antibody

Compound Overview

The At2g04046 Antibody (Product Code: CSB-PA709292XA01DOA) targets the protein product of the AT2G04046 gene in Arabidopsis thaliana. Key specifications include:

This antibody is validated for applications such as Western blotting and ELISA, though peer-reviewed studies confirming its functional use are absent in public databases .

Target Protein Characterization

The AT2G04046 gene encodes a hypothetical protein with no annotated domains or experimentally confirmed functions. Computational analyses suggest it may localize to the cytoplasm, but this remains unverified. Sequence alignment reveals no direct orthologs in other plant species, implying a lineage-specific role .

Research Applications

While no published studies explicitly using the At2g04046 antibody were identified, its potential applications include:

1. Gene Expression Studies: Profiling AT2G04046 protein levels during developmental stages or stress responses.

2. Subcellular Localization: Pairing with GFP-tagged constructs for cellular compartment mapping.

3. Interaction Screens: Identifying binding partners via co-immunoprecipitation.

The lack of commercial epitope information (residues 1–100 immunogen) limits mechanistic studies .

Limitations and Research Gaps

Critical knowledge deficits include:

1. Absence of knockout mutant phenotypes for AT2G04046

2. No crystallographic or NMR structures of the target protein

3. Uncharacterized post-translational modifications

Future Directions

Priority investigations should:

1. Establish tissue-specific expression patterns using immunohistochemistry

2. Conduct phenotypic analyses of CRISPR-edited AT2G04046 mutants

3. Perform structural characterization via cryo-EM