DIR17 Antibody
Description
Table 1: Key Applications of DIR17 Antibody
Key Findings:
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Specificity: The antibody shows high specificity for DIR17 in Arabidopsis, with no cross-reactivity reported in human or murine models .
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Functional Insights: DIR17 may interact with metabolic enzymes like pyruvate dehydrogenase (PDH-E2), suggesting roles in energy balance and stress responses .
Comparative Analysis with Related Antibodies
DIR17 shares structural similarities with other dirigent-family antibodies (e.g., DIR1, DIR23), but its unique antigen-binding sites distinguish it:
| Feature | DIR17 Antibody | DIR1 Antibody | DIR23 Antibody |
|---|---|---|---|
| Target Protein | Q9FIG6 | Q9FIG6 | Q84TH6 |
| Molecular Weight | ~69 kDa | ~68 kDa | ~70 kDa |
| Applications | WB, IF, IHC | WB, ELISA | WB, IF |
Data sourced from Cusabio product listings .
Research Gaps and Future Directions
Despite its utility in plant studies, DIR17 antibody research faces limitations:
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Mechanistic Clarity: The precise role of DIR17 in Arabidopsis signaling pathways requires further elucidation .
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Therapeutic Potential: No studies explore DIR17 in human disease models, unlike cadherin-targeting antibodies (e.g., anti-CDH17 for cancer imaging) .
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Omics Integration: Combining DIR17 studies with metabolomic or transcriptomic datasets could reveal novel regulatory networks .
Product Specs
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
