Y73F4A.2 Antibody
Description
Overview of Y73F4A.2 Antibody
The Y73F4A.2 antibody is a custom research reagent developed to target the Y73F4A.2 protein encoded by the Caenorhabditis elegans gene of the same name. This antibody is cataloged under CSB-PA896443XA01CXY and is primarily utilized in molecular biology and genetic studies involving C. elegans model systems .
Target Protein Information
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Gene: Y73F4A.2
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UniProt ID: Q9XWC3
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Species: Caenorhabditis elegans
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Antibody Type: Polyclonal
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Applications: Immunoprecipitation (IP), Western Blot (WB), Immunofluorescence (IF)
Phenotypic Associations
In a proteomic study analyzing C. elegans mutants, Y73F4A.2 was linked to nuclei enlargement phenotypes (WBPhenotype:0001567). Key experimental data include:
| Metric | Value |
|---|---|
| log2FC | 3.829 |
| P-value | 1.142 |
| t-statistic | 2.428 |
| t-SAM | 1.244 |
This suggests potential roles in chromatin organization or cell cycle regulation .
Comparative Analysis with Related Antibodies
The Y73F4A.2 antibody belongs to a broader category of C. elegans-targeting antibodies. Key comparisons include:
| Antibody Name | Target Protein | UniProt ID | Phenotypic Role |
|---|---|---|---|
| Y73F4A.2 | Y73F4A.2 | Q9XWC3 | Nuclei enlargement |
| K01H12.1 | K01H12.1 | Q21102 | Developmental regulation |
| dpy-27 | dpy-27 | P48996 | Body morphology defects |
Applications in Current Research
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Functional Genomics: Used to study gene silencing effects in C. elegans .
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Protein Localization: Employed in subcellular localization assays via immunofluorescence .
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Disease Modeling: Investigated for roles in chromatin-related disorders due to nuclei enlargement phenotypes .
Limitations and Future Directions
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Specificity: Limited validation in non-C. elegans systems.
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Mechanistic Insights: No structural or pathway-level data available for the target protein.
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Therapeutic Potential: Not explored beyond basic research contexts.
Product Specs
Target Background
KEGG: cel:CELE_Y73F4A.2
UniGene: Cel.5536
