DRP2B Antibody
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In Stock 
Product Specs
Buffer
Preservative: 0.03% ProClin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
DRP2B antibody; ADL3 antibody; CF1 antibody; At1g59610 antibody; T30E16.17Dynamin-2B antibody; EC 3.6.5.5 antibody; Dynamin-like protein 3 antibody; Dynamin-related protein 2B antibody
Target Names
DRP2B
Uniprot No.
Target Background
Function
This antibody targets a putative microtubule-associated, force-producing protein with GTP binding and hydrolysis capabilities. It functions in clathrin-coated vesicle formation during endocytosis, collaborating with DRP1A. In conjunction with DRP1A and PIP5K3, it plays a critical role in precisely coordinating the placement of polar ARAC3/ROP6 and ARAC4/ROP2, ultimately influencing root hair positioning and planar polarity formation in root hair-forming cells.
Gene References Into Functions
Supporting research highlights the following:
- Studies demonstrate that AVR3a variants suppress flg22-triggered defense responses and reduce activated FLS2 internalization. Furthermore, AVR3a interacts with DRP2, a plant GTPase involved in receptor-mediated endocytosis. [DRP2B] PMID: 26348328
- DRP2B is identified as a vesicular trafficking protein contributing to flg22 signaling and PTI in plants. PMID: 25521759
- Arabidopsis dynamin-related proteins, DRP1A and DRP2B, from distinct families, participate in membrane remodeling at the cell plate. [DRP2B] PMID: 18612642
Database Links
Protein Families
TRAFAC class dynamin-like GTPase superfamily, Dynamin/Fzo/YdjA family
Subcellular Location
Cytoplasm, cytoskeleton. Cytoplasmic vesicle, clathrin-coated vesicle. Cell membrane.
Tissue Specificity
Ubiquitous. Preferentially expressed in siliques.
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