DTX8 Antibody

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Description

Introduction to Antibodies

Antibodies, also known as immunoglobulins, are proteins produced by B cells that play a crucial role in the immune system by recognizing and binding to specific antigens. Monoclonal antibodies are produced by a single clone of B cells and are highly specific to their target antigen, making them valuable tools in research, diagnostics, and therapy.

Applications of Monoclonal Antibodies

Monoclonal antibodies are used in various applications, including:

  • Western Blotting: For detecting specific proteins in cell lysates.

  • Immunohistochemistry: For staining tissues to identify specific cell types or proteins.

  • Immunotherapy: Targeting specific cells or proteins to treat diseases like cancer or autoimmune disorders.

Example: TdT Monoclonal Antibody

The TdT monoclonal antibody (7UNA8U6) is an example of a specific antibody used in research. It targets terminal deoxynucleotidyl transferase (TdT), a protein involved in lymphocyte development. This antibody is used for western blotting and immunohistochemistry, particularly in studying lymphoid tissues and diseases like lymphoma or leukemia .

Research Findings and Data

While specific data on "DTX8 Antibody" is not available, research on other antibodies often involves detailed studies on their specificity, sensitivity, and applications. For instance, studies on antibodies targeting tau proteins in neurodegenerative diseases have shown promising results in promoting tau uptake by microglia, which could be beneficial for treating conditions like Alzheimer's disease .

Example Data Table for Antibody Applications

Antibody TypeApplicationConcentration
TdT (7UNA8U6)Western Blot≤ 5 µg/mL
TdT (7UNA8U6)Immunohistochemistry≤ 10 µg/mL
His-Tag AntibodyWestern Blot1:1000
His-Tag AntibodyImmunoprecipitation1:200

Product Specs

Buffer
Preservative: 0.03% ProClin 300; Constituents: 50% Glycerol, 0.01M Phosphate-Buffered Saline (PBS), pH 7.4
Form
Liquid
Lead Time
14-16 week lead time (made-to-order)
Synonyms
DTX8 antibody; At1g66780 antibody; F4N21_9Protein DETOXIFICATION 8 antibody; AtDTX8 antibody; Multidrug and toxic compound extrusion protein 8 antibody; MATE protein 8 antibody
Target Names
DTX8
Uniprot No.

Target Background

Database Links
Protein Families
Multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family
Subcellular Location
Membrane; Multi-pass membrane protein.

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