Antibodies, also known as immunoglobulins, are proteins produced by B cells that play a crucial role in the immune system by recognizing and binding to specific antigens. Monoclonal antibodies are produced by a single clone of B cells and are highly specific to their target antigen, making them valuable tools in research, diagnostics, and therapy.
Monoclonal antibodies are used in various applications, including:
Western Blotting: For detecting specific proteins in cell lysates.
Immunohistochemistry: For staining tissues to identify specific cell types or proteins.
Immunotherapy: Targeting specific cells or proteins to treat diseases like cancer or autoimmune disorders.
The TdT monoclonal antibody (7UNA8U6) is an example of a specific antibody used in research. It targets terminal deoxynucleotidyl transferase (TdT), a protein involved in lymphocyte development. This antibody is used for western blotting and immunohistochemistry, particularly in studying lymphoid tissues and diseases like lymphoma or leukemia .
While specific data on "DTX8 Antibody" is not available, research on other antibodies often involves detailed studies on their specificity, sensitivity, and applications. For instance, studies on antibodies targeting tau proteins in neurodegenerative diseases have shown promising results in promoting tau uptake by microglia, which could be beneficial for treating conditions like Alzheimer's disease .
| Antibody Type | Application | Concentration |
|---|---|---|
| TdT (7UNA8U6) | Western Blot | ≤ 5 µg/mL |
| TdT (7UNA8U6) | Immunohistochemistry | ≤ 10 µg/mL |
| His-Tag Antibody | Western Blot | 1:1000 |
| His-Tag Antibody | Immunoprecipitation | 1:200 |
KEGG: ath:AT1G66780
STRING: 3702.AT1G66780.1