DYN3 Antibody
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In Stock 
Description
Target Protein Overview
Dynamin-3 belongs to the TRAFAC class dynamin-like GTPase superfamily and is involved in:
Key features of dynamin-3:
| Property | Detail |
|---|---|
| Molecular Weight | ~97.7 kDa (calculated) |
| Isoforms | 5 reported variants |
| Gene ID (Human) | DNM3 |
| UniProt ID (Mouse/Rat) | Q8BZ98 (Mouse), Q08877 (Rat) |
Immunogen Design
Technical Parameters
| Parameter | Details |
|---|---|
| Host Species | Rabbit |
| Applications | Western blot (WB), ELISA |
| Dilution Range | WB: 1:500–1:2000; ELISA: 1:5000–1:20,000 |
| Reactive Species | Human, Mouse, Rat |
Western Blot Validation
Functional Studies
-
Used to investigate dynamin-3’s role in:
Limitations and Considerations
-
Species specificity: Limited cross-reactivity beyond human, mouse, and rat
-
Storage: Requires -20°C storage with glycerol stabilizers; sensitive to freeze-thaw cycles
Emerging Research Directions
Recent studies highlight dynamin-3’s involvement in:
Product Specs
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M Phosphate Buffered Saline (PBS), pH 7.4
Constituents: 50% Glycerol, 0.01M Phosphate Buffered Saline (PBS), pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
DYN3 antibody; AGL333WCytoplasmic dynein intermediate light chain DYN3 antibody; Dynein protein 3 antibody
Target Names
DYN3
Uniprot No.
Target Background
Function
This antibody targets DYN3, a component of the cytoplasmic dynein motor complex. Dynein functions in the intracellular retrograde movement of vesicles and organelles along microtubules. It is believed to play a critical role in the proper alignment of the mitotic spindle during cell division in yeast. DYN3 is likely essential for normal cell cycle progression.
Database Links
KEGG: ago:AGOS_AGL333W
STRING: 33169.AAS54158
Protein Families
Dynein light intermediate chain DYN3 family
Subcellular Location
Cytoplasm, cytoskeleton.
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