At4g04760 Antibody

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Description

Structure and Function of Antibodies

Antibodies, also known as immunoglobulins, are Y-shaped glycoproteins produced by B cells in response to antigens. They consist of two heavy chains and two light chains linked by disulfide bonds. The variable regions of these chains, particularly the complementarity-determining regions (CDRs), are responsible for binding to specific epitopes on antigens .

Antibody ComponentFunction
Fab FragmentAntigen binding
Fc FragmentEffector functions, such as complement activation and cell signaling
Hinge RegionProvides flexibility between Fab and Fc regions

Applications of Antibodies in Plant Biology

Antibodies are crucial tools in plant biology for studying protein expression, localization, and function. They are used in techniques such as Western blotting, immunoprecipitation, and immunofluorescence microscopy. For example, antibodies targeting specific plant proteins can help researchers understand their roles in stress responses, development, or metabolic pathways.

Research Findings and Data

While specific data on the "At4g04760 Antibody" is not available, antibodies in general have been instrumental in advancing our understanding of plant biology. For instance, studies using antibodies to investigate protein-protein interactions or post-translational modifications have provided valuable insights into plant signaling pathways.

TechniqueApplicationExample
Western BlotProtein expression analysisStudying stress-induced protein expression changes
ImmunofluorescenceProtein localizationVisualizing the distribution of proteins within plant cells
ImmunoprecipitationProtein-protein interaction studiesIdentifying interacting partners of a target protein

References

  1. Jackson ImmunoResearch. Immunoglobulin structure and function. [Accessed 2023].

  2. medRxiv. Declining prevalence of antibody positivity to SARS-CoV-2. [Accessed 2023].

  3. PLOS ONE. Functional relevance of in vivo half antibody exchange of an IgG4 therapeutic antibody-drug conjugate. [Accessed 2023].

  4. Antibodies-online.com. Structure. [Accessed 2023].

  5. FDA. RabiMabs A novel monoclonal antibody cocktail for post-bite... [Accessed 2023].

  6. PMC. Design, Synthesis, and In Vitro Cytotoxic Studies of Some Novel Arylidene-Hydrazinyl-Thiazoles as Anticancer and Apoptosis-Inducing Agents. [Accessed 2023].

  7. GenScript. Immunoglobulin G | IgG Antibody. [Accessed 2023].

Product Specs

Buffer
Preservative: 0.03% ProClin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
14-16 week lead time (made-to-order)
Synonyms
At4g04760 antibody; T4B21.9Sugar transporter ERD6-like 15 antibody
Target Names
At4g04760
Uniprot No.

Target Background

Function
This antibody targets a sugar transporter.
Database Links

KEGG: ath:AT4G04760

UniGene: At.4040

Protein Families
Major facilitator superfamily, Sugar transporter (TC 2.A.1.1) family
Subcellular Location
Membrane; Multi-pass membrane protein.

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