Antibodies, also known as immunoglobulins, are Y-shaped glycoproteins produced by B cells in response to antigens. They consist of two heavy chains and two light chains linked by disulfide bonds. The variable regions of these chains, particularly the complementarity-determining regions (CDRs), are responsible for binding to specific epitopes on antigens .
| Antibody Component | Function |
|---|---|
| Fab Fragment | Antigen binding |
| Fc Fragment | Effector functions, such as complement activation and cell signaling |
| Hinge Region | Provides flexibility between Fab and Fc regions |
Antibodies are crucial tools in plant biology for studying protein expression, localization, and function. They are used in techniques such as Western blotting, immunoprecipitation, and immunofluorescence microscopy. For example, antibodies targeting specific plant proteins can help researchers understand their roles in stress responses, development, or metabolic pathways.
While specific data on the "At4g04760 Antibody" is not available, antibodies in general have been instrumental in advancing our understanding of plant biology. For instance, studies using antibodies to investigate protein-protein interactions or post-translational modifications have provided valuable insights into plant signaling pathways.
| Technique | Application | Example |
|---|---|---|
| Western Blot | Protein expression analysis | Studying stress-induced protein expression changes |
| Immunofluorescence | Protein localization | Visualizing the distribution of proteins within plant cells |
| Immunoprecipitation | Protein-protein interaction studies | Identifying interacting partners of a target protein |
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FDA. RabiMabs A novel monoclonal antibody cocktail for post-bite... [Accessed 2023].
PMC. Design, Synthesis, and In Vitro Cytotoxic Studies of Some Novel Arylidene-Hydrazinyl-Thiazoles as Anticancer and Apoptosis-Inducing Agents. [Accessed 2023].
GenScript. Immunoglobulin G | IgG Antibody. [Accessed 2023].
KEGG: ath:AT4G04760
UniGene: At.4040