EPS15L1 Antibody

Shipped with Ice Packs
In Stock

Product Specs

Buffer
The antibody is provided in PBS (Phosphate Buffered Saline) with 0.02% Sodium Azide, 50% Glycerol, and a pH of 7.3. It should be stored at -20°C and freeze/thaw cycles should be avoided.
Lead Time
We typically dispatch orders within 1-3 business days of receipt. Delivery times may vary depending on the method of purchase and location. Please contact your local distributor for specific delivery information.
Synonyms
EP15R_HUMAN antibody; epidermal growth factor receptor pathway substrate 15- ike 1 antibody; Epidermal growth factor receptor substrate 15 like 1 antibody; Epidermal growth factor receptor substrate 15-like 1 antibody; epidermal growth factor receptor substrate EPS15R antibody; Eps15 related protein antibody; Eps15-related protein antibody; EPS15L1 antibody; Eps15R antibody
Target Names
Uniprot No.

Target Background

Function
EPS15L1 is a constitutive component of clathrin-coated pits, playing a critical role in receptor-mediated endocytosis. It is involved in the internalization of integrin beta-1 (ITGB1) and transferrin receptor (TFR). While EPS15L1 facilitates the endocytosis of ITGB1 as DAB2-dependent cargo, its involvement in TFR internalization appears to require association with DAB2.
Database Links

HGNC: 24634

KEGG: hsa:58513

STRING: 9606.ENSP00000248070

UniGene: Hs.654639

Subcellular Location
Cell membrane; Peripheral membrane protein. Nucleus. Membrane, coated pit.

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