EREX Antibody

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Description

Introduction to Antibodies

Antibodies, also known as immunoglobulins, are proteins produced by the immune system in response to foreign substances, such as bacteria, viruses, or other pathogens. They are crucial for the body's defense against infections and are widely used in medical research and diagnostics.

Types of Antibodies

There are several types of antibodies, including monoclonal and polyclonal antibodies. Monoclonal antibodies are produced by a single clone of cells and are highly specific to a particular antigen, while polyclonal antibodies are produced by different clones of cells and can recognize multiple epitopes on an antigen.

Applications of Antibodies

Antibodies have numerous applications in medicine and research:

  • Therapeutic Use: Monoclonal antibodies are used to treat various diseases, including cancers and autoimmune disorders.

  • Diagnostic Tools: Antibodies are used in assays to detect specific proteins or antigens in biological samples.

  • Research Tools: They are essential for studying protein function and localization in cells.

Research Findings on Similar Antibodies

While specific information on "EREX Antibody" is not available, research on other antibodies provides valuable insights into their mechanisms and applications.

Example: Anti-Epiregulin EREG Antibody

The anti-epiregulin EREG antibody is an example of a specific antibody used in research. This antibody reacts with human, mouse, and rat epiregulin and is tested in ELISA and IHC applications .

Antibody DetailsDescription
Catalog NumberA06692
Reactive SpeciesHuman, Mouse, Rat
HostRabbit
ApplicationELISA, IHC

Challenges in Antibody Research

The field of antibody research faces challenges such as ensuring specificity and efficacy. Studies have shown that a significant portion of commercial antibodies may not perform as expected, highlighting the need for rigorous characterization and validation .

Future Directions

Advancements in antibody technology, including the development of recombinant antibodies, offer promising solutions for improving specificity and performance. Collaborative efforts between researchers and industry partners are crucial for addressing these challenges and advancing the field .

Product Specs

Buffer
Preservative: 0.03% ProClin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
14-16 week lead time (made-to-order)
Synonyms
EREX antibody; At3g15920 antibody; PX domain-containing protein EREX antibody; Protein ENDOSOMAL RAB EFFECTOR WITH PX-DOMAIN antibody
Target Names
EREX
Uniprot No.

Target Background

Function
This antibody targets a protein that functions as an effector of RABF2A and RABF2B. It plays a role in the vacuolar transport of storage proteins and regulates membrane trafficking to protein storage vacuoles (PSVs). The protein exhibits specific binding affinity for phosphatidylinositol 3-monophosphate (PtdIns3P).
Database Links

KEGG: ath:AT3G15920

STRING: 3702.AT3G15920.1

UniGene: At.38970

Subcellular Location
Cytoplasm, cytosol. Endosome membrane; Peripheral membrane protein.

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