EARLI1 Antibody

Shipped with Ice Packs
In Stock

Product Specs

Buffer
Preservative: 0.03% ProClin 300. Constituents: 50% Glycerol, 0.01M PBS, pH 7.4.
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
EARLI1 antibody; At4g12480 antibody; T1P17.70Lipid transfer protein EARLI 1 antibody; Protein EARLY ARABIDOPSIS ALUMINUM INDUCED 1 antibody; pEARLI1 antibody
Target Names
EARLI1
Uniprot No.

Target Background

Function
EARLI1 is a probable lipid transfer protein (LTP) that may enhance freezing survival. Evidence suggests it plays a role in regulating flowering and lignin biosynthesis. Furthermore, it contributes to germination and early seedling development under low temperature and salt stress conditions, possibly through an abscisic acid (ABA)-dependent mechanism. EARLI1 confers resistance to *Botrytis cinerea* and exhibits antifungal activity against *Saccharomyces cerevisiae*, *B. cinerea*, and *Fusarium oxysporum*, potentially by increasing membrane permeability.
Gene References Into Functions
  • Subcellular localization studies indicate EARLI1 is found in locations consistent with lipid exchange/movement (PMID: 26203923).
  • In vivo expression of secreted EARLI1 in *S. cerevisiae* significantly inhibited yeast cell growth (PMID: 22759515).
  • A proposed bimodular architecture for EARLI1 suggests its proline-rich domain interacts with the cell wall, while the 8CM domain interacts with the plasma membrane to protect cells during freezing stress (PMID: 17786468).
Database Links

KEGG: ath:AT4G12480

STRING: 3702.AT4G12480.1

UniGene: At.3226

Protein Families
Plant LTP family, PEARLI1 subfamily
Subcellular Location
Secreted, cell wall.
Tissue Specificity
Mostly expressed in aerial part of seedlings, and, to a lower extent, in roots. Higher basal levels in early-flowering ecotypes.

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