EXG2 Antibody

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Description

Antibody Characteristics

EXG2 antibodies target the EXG2 protein, which belongs to the glycosyl hydrolase family and functions in hydrolyzing β-1,3-glucans in yeast cell walls. Key features include:

PropertyDetails
Host SpeciesRabbit
ReactivitySpecies-specific: Saccharomyces cerevisiae (Baker’s yeast) or Schizosaccharomyces pombe (Fission yeast)
IsotypeIgG
Purification MethodAntigen-affinity chromatography
ApplicationsELISA, Western Blot (WB)

Target Protein: EXG2 Function

EXG2 is annotated as an exo-1,3-beta-glucanase (EC 3.2.1.58) with roles in:

  • Degrading β-1,3-glucans during yeast cell wall remodeling .

  • Sporulation and stress response in fungal organisms .

Antibody Applications

Validated uses for EXG2 antibodies include:

ApplicationPurposeRecommended Dilution
Western BlotDetecting EXG2 in yeast lysatesNot specified
ELISAQuantifying EXG2 expression levels in fungal samplesNot specified

Research Context

While EXG2 antibodies are niche reagents, their utility is highlighted in:

  • Studies on fungal pathogenesis and antifungal drug development .

  • Investigations into yeast cell wall biosynthesis and degradation mechanisms .

Comparative Notes

EXG2 vs. EXD2 Antibodies
EXG2 antibodies are distinct from EXD2 antibodies (e.g., ), which target the human exonuclease EXD2 involved in DNA repair. Confusion may arise due to naming similarities, but these antibodies recognize entirely different proteins across species.

Limitations and Gaps

  • No peer-reviewed publications directly citing EXG2 antibody use were identified in the provided sources.

  • Validation data (e.g., knockout controls, immunolocalization) are absent in available documentation .

Product Specs

Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M Phosphate Buffered Saline (PBS), pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
EXG2 antibody; YDR261C antibody; YD9320A.12CGlucan 1,3-beta-glucosidase 2 antibody; EC 3.2.1.58 antibody; Exo-1,3-beta-glucanase 2 antibody
Target Names
EXG2
Uniprot No.

Target Background

Database Links

KEGG: sce:YDR261C

STRING: 4932.YDR261C

Protein Families
Glycosyl hydrolase 5 (cellulase A) family
Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor.

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