FAM122B Antibody

Research Applications and Biological Significance

FAM122B antibodies enable critical insights into the protein's role in oncogenesis and cellular processes:

Cancer Biology

• Overexpression Correlation: Elevated FAM122B levels are associated with enhanced cell migration, invasion, and poor prognosis in multiple cancers .

• Metastasis Studies: Antibody-based detection in HCT116 colon cancer cells (ab97797) and mouse brain tissue (PACO37266) confirms its utility in metastasis research .

Subcellular Localization

• Immunohistochemical staining reveals nuclear and cytoplasmic localization in human uterine glandular cells (Abnova PAB19962) .

Protein Interaction Networks

• FAM122B participates in signaling complexes regulating cell growth, as identified through co-immunoprecipitation studies .

Validation and Quality Assurance

Commercial antibodies undergo rigorous validation:

Future Directions

Current research leverages FAM122B antibodies to:

1. Identify therapeutic targets in metastatic cancers

2. Decipher FAM122B’s role in cell cycle regulation

3. Develop multiplex biomarker panels using IHC-based quantification