At3g60790 Antibody

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Description

Nomenclature and Biological Context

  • At3g60790 follows Arabidopsis thaliana gene nomenclature, where "At" denotes the species, "3" indicates chromosome 3, and "g60790" is a locus identifier. No functional annotation for this gene is publicly documented as of March 2025 .

  • Antibodies targeting Arabidopsis proteins are typically developed for studying plant biochemistry, stress responses, or gene-editing validation. Examples include antibodies against lipid metabolism enzymes (e.g., ATGL Antibody ) and stress-response proteins .

Antibody Development Workflow (Hypothetical Framework)

If At3g60790 Antibody were produced, its development would likely follow standardized protocols:

ParameterTypical Methodology
Antigen DesignRecombinant protein or peptide corresponding to At3g60790’s predicted epitopes.
Host SpeciesMouse, rabbit, or chicken (for avian-derived antibodies with unique CDR diversity ).
Cloning & ValidationHybridoma technology or phage display; validated via Western blot (WB), ELISA .
ApplicationsImmunohistochemistry (IHC), protein localization, or phenotypic screening .

Key Challenges in Plant-Targeted Antibody Development

  • Low immunogenicity: Plant proteins may require adjuvant-enhanced immunization .

  • Cross-reactivity: Rigorous tissue cross-reactivity (TCR) studies are critical to avoid off-target binding .

  • Validation: Antibodies must distinguish between homologous isoforms (e.g., ATGL vs. ADPN ).

Research Implications

If developed, At3g60790 Antibody could enable:

  • Functional genomics: Elucidating the role of At3g60790 in Arabidopsis pathways.

  • Agricultural biotechnology: Engineering stress-tolerant crops via protein expression profiling.

  • Structural studies: Mapping conformational epitopes using SPR or cryo-EM .

Gaps and Future Directions

  • No peer-reviewed studies or commercial products reference At3g60790 Antibody, suggesting it may be under development or lack functional relevance.

  • Researchers are advised to:

    1. Confirm the gene’s annotation via TAIR (The Arabidopsis Information Resource).

    2. Partner with antibody vendors for custom synthesis .

    3. Validate using orthogonal methods (e.g., CRISPR knockout lines).

Product Specs

Buffer
Preservative: 0.03% Proclin 300
Composition: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
At3g60790 antibody; T4C21.200F-box protein At3g60790 antibody
Target Names
At3g60790
Uniprot No.

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