At4g22180 Antibody
Description
Introduction to At4g22180 Antibody
The At4g22180 Antibody is a polyclonal antibody specific to the Arabidopsis thaliana protein encoded by the gene locus At4g22180. This antibody is commercially available through Cusabio Biotech Co., Ltd., with the catalog code CSB-PA526191XA01DOA . It is designed for research applications in plant biology, targeting the protein associated with the Uniprot identifier O49624.
Antibody Design and Validation
The development of plant-specific antibodies like At4g22180 involves challenges such as low cross-reactivity with non-target proteins and ensuring compatibility with plant tissue matrices. Modern approaches include:
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Phage Display: A method to engineer high-affinity antibodies by screening combinatorial libraries .
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Single-Cell Analysis: Techniques like CD138+ plasma cell isolation to identify antigen-specific B cells, as demonstrated in COVID-19 research .
Limitations in Current Data
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No Direct Studies: No peer-reviewed articles explicitly detail At4g22180 Antibody’s performance in functional assays (e.g., neutralization or epitope mapping).
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General Antibody Dynamics: Structural studies highlight the role of the constant region in modulating antigen binding, which may influence At4g22180’s specificity .
Comparative Insights from Related Antibodies
Product Specs
Constituents: 50% Glycerol, 0.01M Phosphate Buffered Saline (PBS), pH 7.4
