At2g43260 Antibody

Overview of At2g43260 Antibody

The At2g43260 Antibody (Product Code: CSB-PA854660XA01DOA) is a polyclonal antibody designed to detect the protein product of the At2g43260 gene in Arabidopsis thaliana. This gene is annotated in the UniProt database under accession number Q8S8Q9, though its exact biological function remains under investigation. The antibody is validated for applications such as Western blotting, immunohistochemistry, and immunofluorescence .

Functional Insights from Related Antibody Studies

Antibodies against plant proteins often reveal roles in stress responses, development, or metabolism. Key findings from analogous research include:

• Immune modulation: Antibodies targeting pathogen-associated proteins in plants have been used to study host-microbe interactions .

• Structural insights: High-resolution imaging with antibodies has resolved subcellular localization of regulatory proteins .

• Therapeutic potential: Engineered antibodies in clinical studies (e.g., anti-HIV or anti-cancer antibodies) highlight the broader utility of specificity-driven designs .

Challenges and Considerations

• Specificity validation: Commercial antibodies require rigorous testing to avoid cross-reactivity, as seen in studies criticizing nonspecific angiotensin II receptor antibodies .

• Epitope accessibility: Conformational changes in target proteins may affect antibody binding efficiency .

Future Directions

The At2g43260 Antibody could catalyze studies to:

• Characterize the protein’s role in Arabidopsis stress responses or development.

• Screen mutant libraries for phenotypic changes linked to At2g43260 dysfunction.

• Facilitate structural studies using cryo-EM or X-ray crystallography .