At5g41630 Antibody

Definition and Molecular Target

At5g41630 Antibody is a research-grade monoclonal antibody designed to target the protein encoded by the AT5G41630 gene in Arabidopsis thaliana (mouse-ear cress). This gene belongs to the F-box/RNI-like superfamily, a family of proteins involved in ubiquitin-mediated protein degradation pathways . The antibody is produced for applications in plant biology, particularly for studying protein localization, interaction networks, and functional roles in cellular processes such as cell cycle regulation or stress responses .

The target protein (UniProt ID: Q9FFR7) is annotated as an F-box domain-containing protein, which typically interacts with E3 ubiquitin ligases to mediate substrate recognition for proteasomal degradation .

Functional Context of AT5G41630

The AT5G41630 gene is part of the F-box protein family, which plays roles in:

• Protein turnover: Regulating the stability of transcription factors and signaling molecules.

• Stress responses: Modulating plant adaptation to environmental stresses (e.g., drought, pathogens) .

While no studies directly link At5g41630 Antibody to these pathways, its development aligns with broader efforts to dissect post-translational regulation in plants .

Limitations and Future Directions

• Limited Published Data: No peer-reviewed studies explicitly mention At5g41630 Antibody, highlighting a gap in its application documentation.

• Cross-Reactivity: Potential off-target binding to homologous F-box proteins in Arabidopsis or related species warrants validation.

• Therapeutic Potential: Unlike human-targeted antibodies (e.g., anti-TNFα for rheumatoid arthritis ), At5g41630 Antibody is strictly a research tool.