FRI Antibody

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Product Specs

Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
FRI antibody; At4g00650 antibody; F6N23.25Inactive protein FRIGIDA antibody
Target Names
FRI
Uniprot No.

Target Background

Gene References Into Functions

Gene References and Functions

  1. Data indicate that FRIGIDA protein (FRI) acts as an activator of EARLY FLOWERING IN SHORT DAYS protein EFS (EFS), which in turn functions as a histone H3 Lys36-specific methyltransferase. PMID: 28584923
  2. Natural variations involving deletion alleles modulate temperature-sensitive flowering responses. PMID: 26662639
  3. Structural analysis of FRIGIDA flowering-time regulator. PMID: 26633860
  4. Proteasome-mediated FRI degradation regulates flowering during vernalization in Arabidopsis. PMID: 25538183
  5. Analysis of flowering time data from various Arabidopsis natural accessions suggests that the FRI-Ler allele retains some functionality. PMID: 25207670
  6. Expression of the FRI gene in Arabidopsis thaliana plants under extreme conditions in the northern margins of the species' range. PMID: 25474881
  7. Spatial patterns of FRI, FLC, and PHYC polymorphisms are significantly associated with winter temperatures and spring and winter precipitations, respectively. The allelic variation in these genes is involved in climatic adaptation. PMID: 21988878
  8. Research presents evidence that the FRI (FRIGIDA) gene exhibits 'adaptive' pleiotropy, resulting in trait correlations along an axis that leads to two adaptive strategies. PMID: 23698015
  9. FRI forms a large protein complex that interacts with FLC-specific regulators and recruits chromatin modification factors. PMID: 21282526
  10. FRI and FRL1 contain a stable, central domain that is conserved across the FRI superfamily. PMID: 20405310
  11. The suppression of late flowering is attributed to the inability of FRIgida to increase late flowering. PMID: 15361145
  12. The contribution to variation in flowering time and vernalization of the two genes FRIGIDA (FRI) and FLOWERING LOCUS C (FLC), previously identified as significant determinants in natural variation of flowering time, is reported. PMID: 15908596
  13. FRI upregulates FLC expression, which in turn represses flowering. PMID: 16547097
  14. These antagonistic pleiotropic effects reduce the adaptive value of FRI, helping to explain the maintenance of alternative life history strategies across natural populations of A. thaliana. PMID: 17940010
  15. Natural allelic variation in FRI can mediate response to selection for early flowering. PMID: 19317844
  16. FRI up-regulates FLC expression through a cotranscriptional mechanism involving direct physical interaction with the nuclear cap-binding complex, leading to concomitant effects on FLC transcription and splicing. PMID: 19429606
Database Links

KEGG: ath:AT4G00650

STRING: 3702.AT4G00650.1

UniGene: At.16827

Protein Families
Frigida family
Subcellular Location
Nucleus.

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