Data indicate that FRIGIDA protein (FRI) acts as an activator of EARLY FLOWERING IN SHORT DAYS protein EFS (EFS), which in turn functions as a histone H3 Lys36-specific methyltransferase. PMID: 28584923
Structural analysis of FRIGIDA flowering-time regulator. PMID: 26633860
Proteasome-mediated FRI degradation regulates flowering during vernalization in Arabidopsis. PMID: 25538183
Analysis of flowering time data from various Arabidopsis natural accessions suggests that the FRI-Ler allele retains some functionality. PMID: 25207670
Expression of the FRI gene in Arabidopsis thaliana plants under extreme conditions in the northern margins of the species' range. PMID: 25474881
Spatial patterns of FRI, FLC, and PHYC polymorphisms are significantly associated with winter temperatures and spring and winter precipitations, respectively. The allelic variation in these genes is involved in climatic adaptation. PMID: 21988878
Research presents evidence that the FRI (FRIGIDA) gene exhibits 'adaptive' pleiotropy, resulting in trait correlations along an axis that leads to two adaptive strategies. PMID: 23698015
FRI forms a large protein complex that interacts with FLC-specific regulators and recruits chromatin modification factors. PMID: 21282526
FRI and FRL1 contain a stable, central domain that is conserved across the FRI superfamily. PMID: 20405310
The suppression of late flowering is attributed to the inability of FRIgida to increase late flowering. PMID: 15361145
The contribution to variation in flowering time and vernalization of the two genes FRIGIDA (FRI) and FLOWERING LOCUS C (FLC), previously identified as significant determinants in natural variation of flowering time, is reported. PMID: 15908596
FRI upregulates FLC expression, which in turn represses flowering. PMID: 16547097
These antagonistic pleiotropic effects reduce the adaptive value of FRI, helping to explain the maintenance of alternative life history strategies across natural populations of A. thaliana. PMID: 17940010
Natural allelic variation in FRI can mediate response to selection for early flowering. PMID: 19317844
FRI up-regulates FLC expression through a cotranscriptional mechanism involving direct physical interaction with the nuclear cap-binding complex, leading to concomitant effects on FLC transcription and splicing. PMID: 19429606