G6PD5 Antibody

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In Stock

Product Specs

Buffer
Preservative: 0.03% Proclin 300
Components: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
14-16 Weeks (Made-to-Order)
Synonyms
G6PD5 antibody; ACG9 antibody; At3g27300 antibody; K17E12.12 antibody; Glucose-6-phosphate 1-dehydrogenase 5 antibody; cytoplasmic antibody; AtG6PD5 antibody; G6PDH5 antibody; EC 1.1.1.49 antibody
Target Names
G6PD5
Uniprot No.

Target Background

Function
This antibody targets glucose-6-phosphate dehydrogenase (G6PD), a key enzyme catalyzing the rate-limiting step in the oxidative pentose phosphate pathway. This pathway represents an alternative carbohydrate dissimilation route to glycolysis. G6PD's primary function is to generate NADPH, a crucial reducing agent, and pentose phosphates essential for fatty acid and nucleic acid biosynthesis. These metabolites are vital for membrane synthesis and cell division.
Gene References Into Functions
  • Studies indicate that reduced cytosolic G6PD activity in developing seeds alters metabolism, increasing the availability of carbon substrates for storage compound synthesis. This effect appears to outweigh any decrease in NADPH specifically for fatty acid synthesis. (PMID: 17993547)[PMID: 17993547]
Database Links

KEGG: ath:AT3G27300

STRING: 3702.AT3G27300.1

UniGene: At.25212

Protein Families
Glucose-6-phosphate dehydrogenase family
Subcellular Location
Cytoplasm, cytosol.
Tissue Specificity
Expressed in leaves and stems.

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