GGT4 Antibody

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Description

3.1. Western Blot and ELISA

  • Used to detect cleaved GGT4 in tissues or cell lysates, aiding in studies of protease activity or disease-associated cleavage events .

  • Enables quantification of GGT4/GGT7 expression levels in redox-related pathologies (e.g., cancer, neurodegenerative diseases).

3.2. Limitations in Current Literature

  • No peer-reviewed publications specifically using this antibody are cited in available sources .

  • Broader research on GGT4’s role in disease mechanisms remains sparse compared to other GGT isoforms.

Comparative Analysis with Related Antibodies

FeatureGGT4 AntibodyTypical IgG4 Antibodies
Primary TargetCleaved GGT4 (T472)Immune checkpoints (e.g., PD-1) or allergens
Functional RoleDetects enzymatic cleavageBlocks immune effector responses
Clinical RelevanceUnderstudied in disease modelsLinked to cancer immune evasion

Future Directions

  • Mechanistic Studies: Clarify GGT4’s role in glutathione regulation and its cleavage-dependent activation.

  • Disease Associations: Investigate GGT4 expression in cancers or inflammatory conditions where redox imbalance is prevalent.

  • Therapeutic Potential: Explore antibody utility in diagnostic assays or as a biomarker for oxidative stress-related disorders.

Product Specs

Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M Phosphate Buffered Saline (PBS), pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
GGT4 antibody; GGT3 antibody; At1g69820 antibody; T17F3.15 antibody; Putative inactive glutathione hydrolase 4 antibody; Gamma-glutamyltranspeptidase 3 antibody; Putative inactive gamma-glutamyltranspeptidase 4 antibody
Target Names
GGT4
Uniprot No.

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