GAUT4 Antibody
Description
GAUT4 Function and Biological Role
GAUT4 is a pectin biosynthetic enzyme critical for plant cell wall structure. Key findings include:
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Knockdown in switchgrass reduces cell wall recalcitrance, increasing sugar release (14–15%) and ethanol yield (41–65%) by altering pectin composition .
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Silencing in tomato increases vegetative biomass but reduces fruit starch and pectin content, leading to firmer fruits and lower harvest index .
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Acts coordinately with GAUT7 in homogalacturonan synthesis, impacting cell wall cross-linking and cellulose accessibility .
Comparative Analysis of Pectin-Related GAUTs
Galectin-4 Antibody (Unrelated to GAUT4)
The Human Galectin-4 Antibody (MAB1227) cited in :
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Specificity: Detects human Galectin-4 at ~36 kDa in colon tissue and cancer cell lines (COLO 205, T84, HT-29).
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Applications: Validated in ELISA and Western blot; no cross-reactivity with Galectin-1, -2, -3, -7, or -8.
Research Gaps
No studies in the provided sources describe GAUT4-specific antibodies. For antibody development, future work could target GAUT4’s catalytic domains (e.g., residues 320-420 in Arabidopsis) based on homology to GAUT1:GAUT7 complexes .
Product Specs
Constituents: 50% Glycerol, 0.01M Phosphate Buffered Saline (PBS), pH 7.4
